Although higher-level constructs often fail to explain the mechanisms underlying motivation, we argue that purely mechanistic approaches have limitations. Lower-level neural data help us identify “biologically plausible” mechanisms, while higher-level constructs are critical to formulate measurable behavioral outcomes when constructing computational models. Therefore, we propose that a multi-level, multi-measure approach is required to fully unpack the black box of motivated behavior.

Open peer commentary on the article ““Black Box” Theatre: Second-Order Cybernetics and Naturalism in Rehearsal and Performance” by Tom Scholte. Upshot: What von Foerster accomplished in raising the specter of second-order cybernetics now requires experimental design and the heavy lifting of theory to complete his quest for new ways of thinking. Scholte’s “black box theatre” points to research into non-trivial systems as a formal means of grasping living systems.

This paper explains how to use a new software tool for argument diagramming available free on the Internet, showing especially how it can be used in the classroom to enhance critical thinking in philosophy. The user loads a text file containing an argument into a box on the computer interface, and then creates an argument diagram by dragging lines from one node to another. A key feature is the support for argumentation schemes, common patterns of defeasible reasoning historically know as (...) topics . Several examples are presented, as well as the results of an experiment in using the system with students in a university classroom. (shrink)

Collaboration on the First Edition of Spacetime Physics began in the mid-1960s when Edwin Taylor took a junior faculty sabbatical at Princeton University where John Wheeler was a professor. The resulting text emphasized the unity of spacetime and those quantities (such as proper time, proper distance, mass) that are invariant, the same for all observers, rather than those quantities (such as space and time separations) that are relative, different for different observers. The book has become a standard introduction to relativity. (...) The Second Edition of Spacetime Physics embodies what the authors have learned during an additional quarter century of teaching and research. They have updated the text to reflect the immense strides in physics during the same period and modernized and increased the number of exercises, for which the First Edition was famous. Enrichment boxes provide expanded coverage of intriguing topics. An enlarged final chapter on general relativity includes new material on gravity waves, black holes, and cosmology. The Second Edition of Spacetime Physics provides a new generation of readers with a deep and simple overview of the principles of relativity. (shrink)

Applied ethics, a subdiscipline of philosophy, lends itself to an encyclopedia format because of the many industries and intellectual fields that it encompasses. The Encyclopedia of Applied Ethics is based on twelve major categories, such as Biomedical Ethics and Environmental Ethics. Religious traditions that embody normative beliefs, as well as classical theories of ethics, are explored in a non-judgmental manner. Each of the twelve categories is divided into discrete areas that are covered by 5,000-6,000 word articles. Each of the 281 (...) articles begins with a definition of the subject and includes a table of contents, glossary of key terms, and bibliography. Second- and third- level headings, boxes, sidebars, and the like emphasize the reference-oriented nature of the material. The four volumes are arranged in an A-Z format, with a complete subject index at the end of the last volume. Articles are written by international experts, arranged alphabetically by title, not by subject, and cross-referenced so the reader can locate relevant information in other articles. One of Library Journal's Best Reference Sources for 1997! One of the CHOICE Outstanding Academic Books for 1998! Cross-references appear in each article to refer readers to related information A glossary and bibliography in each article provide readers with tools for learning and creative thinking. (shrink)

The pandemic of SARS-CoV-2 has led to unprecedented changes to society, causing unique problems that call for extraordinary solutions. We consider one such extraordinary proposal: ‘safer infection sites’ that would offer individuals the opportunity to be intentionally infected with SARS-CoV-2, isolate, and receive medical care until they are no longer infectious. Safer infection could have value for various groups of workers and students. Health professionals place themselves at risk of infection daily and extend this risk to their family members and (...) community. Similarly, other essential workers who face workplace exposure must continue their work, even if have high-risk household members and live in fear of infecting. When schools are kept closed because of the fear that they will be sites of significant transmission, children and their families are harmed in multiple ways and college students who are living on campus, whether or not they are attending classes in person, are contributing to high rates of transmission and experiencing high rates of exposure. We consider whether offering safer infection sites to these groups could be ethically defensible and identify the empirical unknowns that would need to resolve before reaching definitive conclusions. This article is not an endorsement of intentional infection with the coronavirus, but rather is meant to spark conversation on the ethics of out-of-the-box proposals. Perhaps most meaningfully, our paper explores the value of control and peace of mind for those among us most impacted by the pandemic: those essential workers risking the most to keep us safe. (shrink)

This article is reprinted with permission from the Journal of African Christian Thought vol. 4 no. 2, December 2001 published by the Akrofi-Kristaller Memorial Centre for Mission Research and Applied Theology, PO Box 76 Akropong-Akuapem, Ghana, e-mailakrofi@africaonline.com.gh. We are grateful to the editor Dr Gillian Bediako.

William Newcomb and Robert Nozick have provided us with the following problem in rational decision-making. There are two boxes, A and B. A contains either a million dollars or nothing. B contains a thousand dollars. I come into the room in which we have the boxes, closed. I must make one of two choices. Either I open A and take whatever money is present, M or O, or I open both and take whatever money is present, M + T or (...) O + T. What is the rational choice for me to make?Nothing unusual is meant by “rational” in this context. We assume that a person making the choice desires as much money as possible. We assume that he will take into account all relevant available information as to what decision will lead to more money. If he believes that doing X will, or is likely to, lead to more money than doing not-X, then he will do X.In the above case, it would seem that the rational choice is both. T is there for the taking, whether or not I get M, and I might as well try for both. (shrink)

Machine generated contents note: Chapter One: Wrong Question, Right Answer -- Exercise 1: Getting right into it -- Exercise 2: Watching your hand -- Exercise 3: Marking practice -- Chapter Two: Realistic Drawing -- Exercise 4: Picking an object to draw -- Exercise 5: Attentive looking -- Exercise 6: Noticing awareness -- Exercise 7: Marking from the sense of sight -- Exercise 8: Simple rendering -- Exercise 9: Try perspective -- Exercise 10: Working inward -- Chapter Three: Systematic Drawing -- (...) Exercise 11: The circular arrow - a visual mantra -- Exercise 12: Improvising between two points and finding the world in between -- Exercise 13: Thought as art -- Exercise 14: All four pixel images -- Exercise 15: Book of compositions -- Chapter Four: Improvisational Drawing -- Exercise 16: Going outside the box -- Exercise 17: Not-breath awareness -- Exercise 18: Growing improvisation -- Exercise 19: Chasing the Coltrane Effect -- Exercise 20: Drawing to reveal inner conditions -- Exercise 21: Noticing Intuition -- Exercise 22: You are the universe drawing -- Chapter Five: Reading the Drawings -- Exercise 23: An exact physical description -- Exercise 24: Feeling the meaning -- Exercise 25: The story we tell ourselves -- Exercise 26: Connecting our story to a larger story -- Chapter Six: The Search for the Source of Creativity -- Exercise 27: Priming the source -- Exercise 28: Sitting still at the origin -- Exercise 29: Embedded sources -- Exercise 30: Mindful of the path -- Chapter Seven: Meta-Drawing -- Exercise 31: Sharing with yourself -- Exercise 32: Sharing with a trusted friend -- Exercise 33: Sharing with the world. (shrink)

Build the skills you need to understand and resolve ethical problems! Ethical Dimensions in the Health Professions, 7th Edition provides a solid foundation in ethical theory and concepts, applying these principles to the ethical issues surrounding health care today. It uses a unique, six-step decision-making process as a framework for thinking critically and thoughtfully, with case studies of patients to illustrate ethical topics such as conflict of interest, patient confidentiality, and upholding best practices. Written by Regina F. Doherty, an educator (...) and occupational therapist, this book will help you make caring and effective ethical choices that improve patient care and outcomes. UNIQUE! Ethical decision-making process provides an organizing framework to use in making the best decisions when faced with ethical problems. Patient stories depict real-life situations and demonstrate the ethical decision-making process. Reflection boxes depict important concepts and stimulate critical thinking. Summary boxes highlight the most important information in each section. Coverage of interprofessional team decision-making reflects this important, expanding movement in healthcare nationally and internationally. Questions for thought and discussion encourage students to apply the ethical decision-making process to different situations. NEW! Updated content throughout the book reflects the changes in the growing interprofessional movement. NEW! Expanded content on clinician well-being includes tools for supporting moral resilience and preventing burnout in health professionals. NEW! Updated content addresses the topics of social justice, health disparities, intersectionality, and health outcomes. NEW! Updated national standards and regulations are provided for electronic health communications, data protections, and clinical research. NEW! Coverage of scientific literature is expanded with studies on the effects of compassion on patient outcomes, patient safety, and provider and organizational well-being. NEW! Coverage of ethical issues impacting healthcare and society includes topics such as medical scarcity due to healthcare supply chain shortages and extreme weather events due to climate change. (shrink)

Plant MADS‐box genes encode transcriptional regulators that are critical for a number of developmental processes. In the angiosperms (the flowering plants), these include the specification of floral organ identities, flowering time and fruit development. It appears that the MADS box gene family has undergone considerable gene duplication and sequence divergence within the angiosperms. Here I discuss the possibility that these events have allowed the recruitment of these genes to new developmental pathways in particular angiosperm lineages. Recent analyses of sequence changes, (...) expression patterns and, in a few cases, gene function are beginning to provide tantalizing evidence for deciphering when and how such genetic diversification has led to particular morphological innovations. In the future, comparative studies of large numbers of species will be required to assess the extent of such variation as well as to fully understand the mechanisms by which evolution of these developmental regulators has played a role in shaping new morphologies. BioEssays 25:637–646, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

It is argued that current attempts to model human learning behavior commonly fail on one of two counts: either the model assumptions are artificially restricted so as to permit the application of mathematical techniques in deriving their consequences, or else the required complex assumptions are imbedded in computer programs whose technical details obscure the theoretical content of the model. The first failing is characteristic of so-called mathematical models of learning, while the second is characteristic of computer simulation models. An approach (...) to model building which avoids both these failings is presented under the title of a black-box theory of learning. This method permits the statement of assumptions of any desired complexity in a language which clearly exhibits their theoretical content.Section II of the paper is devoted to the problem of testing and comparing alternative learning theories. The policy advocated is to abandon attempts at hypothesis testing. It is argued that, in general, we not only lack sufficient data and sufficiently powerful techniques to test hypotheses, but that the truth of a model is not really the issue of basic interest. A given model may be true in the sense that on the basis of available evidence we cannot statistically reject it, but not interesting in the sense that it provides little information about the processes underlying behavior. Rather, we should accept or reject models on the basis of how much information they provide about the way in which subjects respond to environmental structure. This attitude toward model testing is made precise by introducing a formal measure of the information content of a model. Finally, it is argued that the statistical concept of degrees-of-freedom is misleading when used in the context of model testing and should be replaced by a measure of the information absorbed from the data in estimating parameters. (shrink)

The multistep pathway of eukaryotic gene expression involves a series of highly regulated events in the nucleus and cytoplasm. In the nucleus, genes are transcribed into pre‐messenger RNAs which undergo a series of nuclear processing steps. Mature mRNAs are then transported to the cytoplasm, where they are translated into protein and degraded at a rate dictated by transcript‐ and cell‐type‐specific cues. Until recently, these individual nuclear and cytoplasmic events were thought to be primarily regulated by different RNA‐ and DNA‐binding proteins (...) that are localized either only in the nucleus or only the cytoplasm. Here, we describe multifunctional proteins that control both nuclear and cytoplasmic steps of gene expression. One such class of multifunctional proteins (e.g., Bicoid and Y‐box proteins) regulates both transcription and translation whereas another class (e.g., Sex‐lethal) regulates both nuclear RNA processing and translation. Other events controlled by multifunctional proteins include assembly of spliceosome components, spliceosome recycling, RNA editing, cytoplasmic mRNA localization, and cytoplasmic RNA stability. The existence of multifunctional proteins may explain the paradoxical involvement of the nucleus in an RNA surveillance pathway (nonsense‐mediated decay) that detects cytoplasmic signals (premature termination codons). We speculate that shuttling multifunctional proteins serve to efficiently link RNA metabolism in the cytoplasmic and nuclear compartments. BioEssays 23:775–787, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

Techniques from artificial intelligence (AI) can be used in forensic evidence evaluation and are currently applied in biometric fields. However, it is generally not possible to fully understand how and why these algorithms reach their conclusions. Whether and how we should include such ‘black box’ algorithms in this crucial part of the criminal law system is an open question that has not only scientific but also ethical, legal, and philosophical angles. Ideally, the question should be debated by people with diverse (...) backgrounds. Here, we present a view on the question from the philosophy of science angle: computational reliabilism (CR). CR posits that we are justified in believing the output of an AI system, if we have grounds for believing its reliability. Under CR, these grounds are classified into ‘reliability indicators’ of three types: technical, scientific, and societal. This framework enables debates on the suitability of AI methods for forensic evidence evaluation that take a wider view than explainability and validation. We argue that we are justified in believing the AI’s output for forensic comparison of voices and forensic comparison of faces. Technical indicators include the validation of the AI algorithm in itself, validation of its application in the forensic setting, and case-based validation. Scientific indicators include the simple notion that we know faces and voices contain identifying information along with operationalizing well-established metrics and forensic practices. Societal indicators are the emerging scientific consensus on the use of these methods, as well as their application and interpretation by well-educated and certified practitioners. We expect expert witnesses to rely more on technical indicators to be justified in believing AIsystems, and triers-of-fact to rely more on societal indicators to believe the expert witness supported by the AIsystem. (shrink)

Some physicians, in their care of patients at risk of misusing opioids, use machine learning (ML)-based prediction drug monitoring programmes (PDMPs) to guide their decision making in the prescription of opioids. This can cause a conflict: a PDMP Score can indicate a patient is at a high risk of opioid abuse while a patient expressly reports oppositely. The prescriber is then left to balance the credibility and trust of the patient with the PDMP Score. Pozzi1 argues that a prescriber who (...) downgrades the credibility of a patient’s testimony based on a low PDMP Score is epistemically and morally unjustified and contributes to a form of testimonial injustice. This results in patients being silenced, excluded from decision-making processes and subjected to structural injustices. Additionally, the use of ML systems in medical practices raises concerns about perpetuating existing inequalities, overestimating their capabilities and displacing human authority. However, almost the very same critiques apply to human-based systems. Formalisation, ML systems included, should instead be viewed positively,2 and precisely as a powerful means to begin eroding these and other problems in ethically sensitive domains. In this case, the epistemic virtues of formalisation include promoting transparency, consistency and replicability in decision making. Rigorous ML systems can also help ensure that models …. (shrink)

Cullin‐RING ligases (CRLs) are central regulators of environmental and cellular stress responses, orchestrating diverse processes through the ubiquitination of substrate proteins. As modular complexes, CRLs employ substrate‐specific adaptors to target proteins for degradation and other ubiquitin‐mediated processes, enabling dynamic adaptation to environmental cues. Recent advances have highlighted the largest CRL subfamily SCF (Skp1‐cullin‐F‐box) in environmental sensing, a role historically underappreciated for SCF ubiquitin ligases. Notably, emerging evidence suggests that the F‐box domain, a 50‐amino acid motif traditionally recognized for mediating protein‐protein (...) interactions, can act as a direct environmental sensor due to its ability to bind heavy metals. Despite these advances, the roles of many CRL components in environmental sensing remain poorly understood. This review provides an overview of CRLs in stress response regulation and emphasizes the emerging functions of F‐box proteins in environmental adaptation. (shrink)

Abstract Medical futility is commonly understood as treatment that would not provide for any meaningful benefit for the patient. While the medical facts will help to determine what is medically appropriate, it is often difficult for patients, families, surrogate decision-makers and healthcare providers to navigate these difficult situations. Often communication breaks down between those involved or reaches an impasse. This paper presents a set of practical strategies for dealing with cases of perceived medical futility at a major cancer center. Content (...) Type Journal Article Pages 1-8 DOI 10.1007/s10730-011-9168-3 Authors Colleen M. Gallagher, Section for Integrated Ethics in Cancer Care, Unit 1430, The University of Texas MD Anderson Cancer Center, P.O. Box 301402, Houston, TX 77230-1402, USA Ryan F. Holmes, St. Louis University, St. Louis, MO, USA Journal HEC Forum Online ISSN 1572-8498 Print ISSN 0956-2737. (shrink)

A well-known open problem in epistemic logic is to give a syntactic characterization of the successful formulas. Semantically, a formula is successful if and only if for any pointed model where it is true, it remains true after deleting all points where the formula was false. The classic example of a formula that is not successful in this sense is the “Moore sentence” p ∧ ¬ BOX p, read as “p is true but you do not know p.” Not only (...) is the Moore sentence unsuccessful, it is self-refuting, for it never remains true as described. We show that in logics of knowledge and belief for a single agent (extended by S5), Moorean phenomena are the source of all self-refutation; moreover, in logics for an introspective agent (extending KD45), Moorean phenomena are the source of all unsuccessfulness as well. This is a distinctive feature of such logics, for with a non-introspective agent or multiple agents, non-Moorean unsuccessful formulas appear. We also consider how successful and self-refuting formulas relate to the Cartesian and learnable formulas, which have been discussed in connection with Fitch’s “paradox of knowability.” We show that the Cartesian formulas are exactly the formulas that are not eventually self-refuting and that not all learnable formulas are successful. In an appendix, we give syntactic characterizations of the successful and the self-refuting formulas. (shrink)

A well-known open problem in epistemic logic is to give a syntactic characterization of the successful formulas. Semantically, a formula is successful if and only if for any pointed model where it is true, it remains true after deleting all points where the formula was false. The classic example of a formula that is not successful in this sense is the “Moore sentence” p ∧ ¬ BOX p, read as “p is true but you do not know p.” Not only (...) is the Moore sentence unsuccessful, it is self-refuting, for it never remains true as described. We show that in logics of knowledge and belief for a single agent (extended by S5), Moorean phenomena are the source of all self-refutation; moreover, in logics for an introspective agent (extending KD45), Moorean phenomena are the source of all unsuccessfulness as well. This is a distinctive feature of such logics, for with a non-introspective agent or multiple agents, non-Moorean unsuccessful formulas appear. We also consider how successful and self-refuting formulas relate to the Cartesian and learnable formulas, which have been discussed in connection with Fitch’s “paradox of knowability.” We show that the Cartesian formulas are exactly the formulas that are not eventually self-refuting and that not all learnable formulas are successful. In an appendix, we give syntactic characterizations of the successful and the self-refuting formulas. (shrink)

In 2009 Alexandra Rutherford presented readers with a much-needed post-revisionist interpretation of the the behaviorist movement by elucidating the ways in which social context affected popular acceptance of, and resistance to, the central tenants of B.F. Skinner’s psychological theories. By outlining the ways in which American culture both facilitated and hindered behaviorism success, Rutherford's "Beyond the Box: B.F. Skinnner's technology of behavior from laboratory to life, 1950s-1970s" provides an alternative to strictly intellectual histories of behaviorism by examining how technological approaches (...) to behaviour were employed within a multitude of public forums, and emphasizing the importance of changing American attitudes towards technology, consumer culture and ethics. (shrink)

Peer review is an important component of scholarly research. Long a black box whose practical mechanisms were unknown to researchers and readers, peer review is increasingly facing demands for accountability and improvement. Numerous studies address empirical aspects of the peer review process. Much less consideration is typically given to normative dimensions of peer review. This paper considers what authors, editors, reviewers, and readers ought to expect from the peer review process. Integrity in the review process is vital if various parties (...) are to have trust, or faith, in the credibility of peer review mechanisms. Trust in the quality of peer review can increase or diminish in response to numerous factors. Five core elements of peer review are identified. Constitutive elements of scholarly peer review include: fairness in critical analysis of manuscripts; the selection of appropriate reviewers with relevant expertise; identifiable, publicly accountable reviewers; timely reviews, and helpful critical commentary. The F.A.I.T.H. model provides a basis for linking conceptual analysis of the core norms of peer review with empirical research into the adequacy and effectiveness of various processes of peer review. The model is intended to describe core elements of high-quality peer review and suggest what factors can foster or hinder trust in the integrity of peer review. (shrink)

We extend the notion of absolute convergence for real series in several variables to a notion of convergence for series in a power series field ℝ((t Γ)) with coefficients in ℝ. Subsequently, we define a natural notion of analytic function at a point of ℝ((t Γ))m. Then, given a real function f analytic on a open box I of ℝ m , we extend f to a function f ★ which is analytic on a subset of ℝ((t Γ)) m containing (...) I. We prove that the functions f ★ share with real analytic functions certain basic properties: they are , they have usual Taylor development, they satisfy the inverse function theorem and the implicit function theorem. (shrink)

Ecological fitness has been suggested to provide a unifying definition of fitness. However, a metric for this notion of fitness was in most cases unavailable except by proxy with differential reproductive success. In this article, I show how differential persistence of lineages can be used as a way to assess ecological fitness. This view is inspired by a better understanding of the evolution of some clonal plants, colonial organisms, and ecosystems. Differential persistence shows the limitation of an ensemblist noncausal understanding (...) of evolution. Causal explanations are necessary to understand the evolution by natural selection of these biological systems. †To contact the author write to: Department of Philosophy, University of Montreal, P.O. Box 6128, Station Centre‐Ville, Montreal, Quebec, H3C 3J7 Canada; e‐mail: f.bouchard@umontreal.ca. (shrink)

Chemotherapy is an important therapeutic approach for cancer treatment. However, drug resistance is an obstacle that often impairs the successful use of chemotherapies. Therefore, overcoming drug resistance would lead to better therapeutic outcomes for cancer patients. Recently, studies by our own and other groups have demonstrated that there is an intimate correlation between the loss of the F‐box and WD repeat domain‐containing 7 (FBW7) tumor suppressor and the incurring drug resistance. While loss of FBW7 sensitizes cancer cells to certain drugs, (...) FBW7‐/‐ cells are more resistant to other types of chemotherapies. FBW7 exerts its tumor suppressor function by promoting the degradation of various oncoproteins that regulate many cellular processes, including cell cycle progression, cellular metabolism, differentiation, and apoptosis. Since loss of the FBW7 tumor suppressor is linked to drug resistance, FBW7 may represent a novel therapeutic target to increase drug sensitivity of cancer cells to conventional chemotherapeutics. This paper thus focuses on the new functional aspects of FBW7 in drug resistance. (shrink)

Preface, by N. Foerster.--The pretensions of science, by L. T. More.--Humanism: an essay at definition, by I. Babbitt.--The humility of common sense, by P. E. More.--The pride of modernity, by G. R. Elliott.--Religion without humanism, by T. S. Eliot.--The plight of our arts, by F. J. Mather, Jr.--The dilemma of modern tragedy, by A. R. Thompson.--An American tragedy, by R. Shafer.--Pandora's box in American fiction, by H. H. Clark.--Dionysus in dismay, by S. P. Chase.--Our critical spokesmen, by G. B. Munson.--Behaviour (...) and continuity, by B. Bandler, II.--The well of discipline, by S. B. Gass.--Courage and education, by R. L. Brown.--A list of books (p. 291-294). (shrink)

Published by The Liturgical Press, St. John's Abbey, Box 7500, Collegeville, MN 56321-7500. Annotation copyright by Book News, Inc., Portland, OR.

F N Dunlop; Education and Human Nature, Journal of Philosophy of Education, Volume 4, Issue 1, 30 May 2006, Pages 21–44, https://doi.org/10.1111/j.1467-9752.197.

Following a proposal of Humberstone, this paper studies a semantics for modal logic based on partial “possibilities” rather than total “worlds.” There are a number of reasons, philosophical and mathematical, to find this alternative semantics attractive. Here we focus on the construction of possibility models with a finitary flavor. Our main completeness result shows that for a number of standard modal logics, we can build a canonical possibility model, wherein every logically consistent formula is satisfied, by simply taking each individual (...) finite formula (modulo equivalence) to be a possibility, rather than each infinite maximally consistent set of formulas as in the usual canonical world models. Constructing these locally finite canonical models involves solving a problem in general modal logic of independent interest, related to the study of adjoint pairs of modal operators: for a given modal logic L, can we find for every formula phi a formula f(phi) such that for every formula psi, phi -> BOX psi is provable in L if and only if f(phi) -> psi is provable in L? We answer this question for a number of standard modal logics, using model-theoretic arguments with world semantics. This second main result allows us to build for each logic a canonical possibility model out of the lattice of formulas related by provable implication in the logic. (shrink)

The question of Theodicy demands a reasonable justification of the nature, structures and goals of evil and suffering in the world. The paper attempts to explain the reasons for its presence in our lives and seeks to unveil its principles. If God is all knowing, almighty and also merciful, we must face the problem of the presence of evil and suffering in this world. The main goal of the paper is to show the way the New Testament deals with this (...) question, and further to show to what extent it has influenced the life of Christians from the point of view of teleology. (shrink)

Purpose: Appreciating the relationship between Sylvio Ceccato and Ernst von Glasersfeld, both as people and in their work. Approach: historical and personal accounts, archeological approach to written evidence. Findings: Ceccato’s work is introduced to an English speaking audience, and the roots of Glasersfeld’s work in Ceccato’s is explored. Flaws in Ceccato’s approach are indicated, together with how Glasersfeld’s work overcomes these, specially in language and automatic translation, and what became Radical Constructivism. Conclusion: Glasersfeld willingly acknowledges Ceccato, who he still refers (...) to as the Master. But Ceccato’s work is little known, specially in the English speaking world. The introduction, critique and delineation of extension and resolution of Ceccato’s ideas in Glasersfeld’s work is the intended value of the paper. (shrink)